Title |
Changes in motor cortex excitability associated with temporal repetitive transcranial magnetic stimulation in tinnitus: hints for cross-modal plasticity?
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Published in |
BMC Neuroscience, June 2014
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DOI | 10.1186/1471-2202-15-71 |
Pubmed ID | |
Authors |
Martin Schecklmann, Michael Landgrebe, Tobias Kleinjung, Elmar Frank, Philipp G Sand, Rainer Rupprecht, Peter Eichhammer, Göran Hajak, Berthold Langguth |
Abstract |
Motor cortex excitability was found to be changed after repetitive transcranial magnetic stimulation (rTMS) of the temporal cortex highlighting the occurrence of cross-modal plasticity in non-invasive brain stimulation. Here, we investigated the effects of temporal low-frequency rTMS on motor cortex plasticity in a large sample of tinnitus patients. In 116 patients with chronic tinnitus different parameters of cortical excitability were assessed before and after ten rTMS treatment sessions. Patients received one of three different protocols all including 1 Hz rTMS over the left temporal cortex. Treatment response was defined as improvement by at least five points in the tinnitus questionnaire (TQ). Variables of interest were resting motor threshold (RMT), short-interval intra-cortical inhibition (SICI), intracortical facilitation (ICF), and cortical silent period (CSP). |
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Mendeley readers
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Serbia | 1 | 2% |
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Researcher | 12 | 18% |
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Student > Ph. D. Student | 5 | 8% |
Student > Postgraduate | 4 | 6% |
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Other | 6 | 9% |
Unknown | 16 | 24% |