Title |
DiScRIBinATE: a rapid method for accurate taxonomic classification of metagenomic sequences
|
---|---|
Published in |
BMC Bioinformatics, October 2010
|
DOI | 10.1186/1471-2105-11-s7-s14 |
Pubmed ID | |
Authors |
Tarini Shankar Ghosh, Monzoorul Haque M, Sharmila S Mande |
Abstract |
In metagenomic sequence data, majority of sequences/reads originate from new or partially characterized genomes, the corresponding sequences of which are absent in existing reference databases. Since taxonomic assignment of reads is based on their similarity to sequences from known organisms, the presence of reads originating from new organisms poses a major challenge to taxonomic binning methods. The recently published SOrt-ITEMS algorithm uses an elaborate work-flow to assign reads originating from hitherto unknown genomes with significant accuracy and specificity. Nevertheless, a significant proportion of reads still get misclassified. Besides, the use of an alignment-based orthology step (for improving the specificity of assignments) increases the total binning time of SOrt-ITEMS. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Cameroon | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Brazil | 5 | 5% |
United States | 4 | 4% |
France | 2 | 2% |
Spain | 2 | 2% |
United Kingdom | 2 | 2% |
India | 1 | <1% |
Sweden | 1 | <1% |
Italy | 1 | <1% |
Argentina | 1 | <1% |
Other | 3 | 3% |
Unknown | 88 | 80% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 30 | 27% |
Researcher | 30 | 27% |
Student > Master | 15 | 14% |
Student > Bachelor | 7 | 6% |
Student > Doctoral Student | 5 | 5% |
Other | 17 | 15% |
Unknown | 6 | 5% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 69 | 63% |
Computer Science | 14 | 13% |
Biochemistry, Genetics and Molecular Biology | 13 | 12% |
Mathematics | 2 | 2% |
Nursing and Health Professions | 1 | <1% |
Other | 5 | 5% |
Unknown | 6 | 5% |