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Genome-wide expression profile of the response to spinal cord injury in Xenopus laevis reveals extensive differences between regenerative and non-regenerative stages

Overview of attention for article published in Neural Development, May 2014
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Title
Genome-wide expression profile of the response to spinal cord injury in Xenopus laevis reveals extensive differences between regenerative and non-regenerative stages
Published in
Neural Development, May 2014
DOI 10.1186/1749-8104-9-12
Pubmed ID
Authors

Dasfne Lee-Liu, Mauricio Moreno, Leonardo I Almonacid, Víctor S Tapia, Rosana Muñoz, Javier von Marées, Marcia Gaete, Francisco Melo, Juan Larraín

Abstract

Xenopus laevis has regenerative and non-regenerative stages. As a tadpole, it is fully capable of functional recovery after a spinal cord injury, while its juvenile form (froglet) loses this capability during metamorphosis. We envision that comparative studies between regenerative and non-regenerative stages in Xenopus could aid in understanding why spinal cord regeneration fails in human beings.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 124 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Chile 2 2%
Argentina 1 <1%
Brazil 1 <1%
Unknown 120 97%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 27 22%
Student > Ph. D. Student 22 18%
Researcher 19 15%
Student > Master 11 9%
Student > Doctoral Student 8 6%
Other 18 15%
Unknown 19 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 42 34%
Biochemistry, Genetics and Molecular Biology 33 27%
Neuroscience 9 7%
Medicine and Dentistry 5 4%
Chemistry 3 2%
Other 11 9%
Unknown 21 17%