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Quality assessment of diagnostic before-after studies: development of methodology in the context of a systematic review

Overview of attention for article published in BMC Medical Research Methodology, January 2009
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Title
Quality assessment of diagnostic before-after studies: development of methodology in the context of a systematic review
Published in
BMC Medical Research Methodology, January 2009
DOI 10.1186/1471-2288-9-3
Pubmed ID
Authors

Catherine A Meads, Clare F Davenport

Abstract

Quality assessment tools for primary studies of test accuracy are relatively well developed, although only one is validated (QUADAS), but very little work has been done to develop tools to quality-assess studies evaluating the impact of diagnostic testing on management of patients (diagnostic or therapeutic yield). The recent draft NICE Guide to the Methods of Technology Appraisal (2007) suggests QUADAS "as a useful starting point for appraising studies that evaluate the sensitivity and specificity of a test" but does not mention how to quality assess diagnostic or therapeutic yield studies, in particular diagnostic before-after studies. In the context of undertaking a rapid systematic review of structural neuroimaging in psychosis for NICE, we describe the modifications that we made to QUADAS, our experience of this in practice and in relation to published theory on diagnostic or therapeutic yield studies.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 4 8%
Netherlands 1 2%
Australia 1 2%
Unknown 42 88%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 21%
Student > Ph. D. Student 7 15%
Other 5 10%
Student > Master 5 10%
Student > Postgraduate 3 6%
Other 12 25%
Unknown 6 13%
Readers by discipline Count As %
Medicine and Dentistry 22 46%
Agricultural and Biological Sciences 4 8%
Social Sciences 4 8%
Nursing and Health Professions 3 6%
Business, Management and Accounting 2 4%
Other 4 8%
Unknown 9 19%