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Reduction of exacerbations by the PDE4 inhibitor roflumilast - the importance of defining different subsets of patients with COPD

Overview of attention for article published in Respiratory Research, December 2011
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127 Mendeley
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1 CiteULike
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Title
Reduction of exacerbations by the PDE4 inhibitor roflumilast - the importance of defining different subsets of patients with COPD
Published in
Respiratory Research, December 2011
DOI 10.1186/1465-9921-12-18
Pubmed ID
Authors

Stephen I Rennard, Peter MA Calverley, Udo M Goehring, Dirk Bredenbröker, Fernando J Martinez

Abstract

As chronic obstructive pulmonary disease (COPD) is a heterogeneous disease it is unlikely that all patients will benefit equally from a given therapy. Roflumilast, an oral, once-daily phosphodiesterase 4 inhibitor, has been shown to improve lung function in moderate and severe COPD but its effect on exacerbations in unselected populations was inconclusive. This led to the question of whether a responsive subset existed that could be investigated further.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 127 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 2%
Germany 1 <1%
Canada 1 <1%
Unknown 123 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 28 22%
Other 20 16%
Student > Ph. D. Student 11 9%
Student > Bachelor 11 9%
Professor > Associate Professor 10 8%
Other 32 25%
Unknown 15 12%
Readers by discipline Count As %
Medicine and Dentistry 59 46%
Agricultural and Biological Sciences 14 11%
Pharmacology, Toxicology and Pharmaceutical Science 8 6%
Biochemistry, Genetics and Molecular Biology 7 6%
Economics, Econometrics and Finance 5 4%
Other 12 9%
Unknown 22 17%