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Transcripts that associate with the RNA binding protein, DEAD-END (DND1), in embryonic stem (ES) cells

Overview of attention for article published in BMC Molecular and Cell Biology, August 2011
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Title
Transcripts that associate with the RNA binding protein, DEAD-END (DND1), in embryonic stem (ES) cells
Published in
BMC Molecular and Cell Biology, August 2011
DOI 10.1186/1471-2199-12-37
Pubmed ID
Authors

Rui Zhu, Michelina Iacovino, Elisabeth Mahen, Michael Kyba, Angabin Matin

Abstract

The RNA binding protein, DEAD END (DND1), is essential for maintaining viable germ cells in vertebrates. It is also a testicular germ cell tumor susceptibility factor in mice. DND1 has been shown to interact with the 3'-untranslated region (3'-UTR) of mRNAs such as P27 and LATS2. Binding of DND1 to the 3'-UTRs of these transcripts blocks the inhibitory function of microRNAs (miRNA) from these transcripts and in this way DND1 helps maintain P27 and LATS2 protein expression. We found that DND1 is also expressed in embryonic stem (ES) cells. Because ES cells share similar gene expression patterns as germ cells, we utilized ES cells to identify additional candidate mRNAs that associate with DND1.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 6%
Japan 1 2%
Unknown 44 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 31%
Researcher 10 21%
Student > Postgraduate 4 8%
Student > Bachelor 3 6%
Professor > Associate Professor 3 6%
Other 10 21%
Unknown 3 6%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 20 42%
Agricultural and Biological Sciences 14 29%
Medicine and Dentistry 6 13%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Psychology 1 2%
Other 3 6%
Unknown 3 6%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 August 2011.
All research outputs
#17,285,036
of 25,373,627 outputs
Outputs from BMC Molecular and Cell Biology
#778
of 1,233 outputs
Outputs of similar age
#94,819
of 133,392 outputs
Outputs of similar age from BMC Molecular and Cell Biology
#13
of 21 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,233 research outputs from this source. They receive a mean Attention Score of 4.0. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 133,392 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 21 others from the same source and published within six weeks on either side of this one. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.