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Anti-MPER antibodies with heterogeneous neutralization capacity are detectable in most untreated HIV-1 infected individuals

Overview of attention for article published in Retrovirology, June 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • High Attention Score compared to outputs of the same age and source (81st percentile)

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3 X users
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2 patents

Citations

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19 Dimensions

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36 Mendeley
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Title
Anti-MPER antibodies with heterogeneous neutralization capacity are detectable in most untreated HIV-1 infected individuals
Published in
Retrovirology, June 2014
DOI 10.1186/1742-4690-11-44
Pubmed ID
Authors

Luis M Molinos-Albert, Jorge Carrillo, Marta Curriu, Maria L Rodriguez de la Concepción, Silvia Marfil, Elisabet García, Bonaventura Clotet, Julià Blanco

Abstract

The MPER region of the HIV-1 envelope glycoprotein gp41 is targeted by broadly neutralizing antibodies. However, the localization of this epitope in a hydrophobic environment seems to hamper the elicitation of these antibodies in HIV infected individuals.We have quantified and characterized anti-MPER antibodies by ELISA and by flow cytometry using a collection of mini gp41-derived proteins expressed on the surface of 293T cells. Longitudinal plasma samples from 35 HIV-1 infected individuals were assayed for MPER recognition and MPER-dependent neutralizing capacity using HIV-2 viruses engrafted with HIV-1 MPER sequences.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 36 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 33%
Student > Ph. D. Student 7 19%
Student > Master 5 14%
Professor > Associate Professor 3 8%
Professor 3 8%
Other 6 17%
Readers by discipline Count As %
Immunology and Microbiology 11 31%
Agricultural and Biological Sciences 9 25%
Biochemistry, Genetics and Molecular Biology 6 17%
Medicine and Dentistry 3 8%
Chemistry 3 8%
Other 4 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 March 2018.
All research outputs
#4,718,129
of 25,613,746 outputs
Outputs from Retrovirology
#217
of 1,274 outputs
Outputs of similar age
#43,209
of 243,696 outputs
Outputs of similar age from Retrovirology
#6
of 27 outputs
Altmetric has tracked 25,613,746 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,274 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 243,696 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.