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Effect of a Herbal-Leucine mix on the IL-1β-induced cartilage degradation and inflammatory gene expression in human chondrocytes

Overview of attention for article published in BMC Complementary Medicine and Therapies, August 2011
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (84th percentile)
  • Good Attention Score compared to outputs of the same age and source (72nd percentile)

Mentioned by

twitter
8 X users
patent
1 patent
facebook
1 Facebook page
googleplus
1 Google+ user

Citations

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39 Dimensions

Readers on

mendeley
70 Mendeley
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Title
Effect of a Herbal-Leucine mix on the IL-1β-induced cartilage degradation and inflammatory gene expression in human chondrocytes
Published in
BMC Complementary Medicine and Therapies, August 2011
DOI 10.1186/1472-6882-11-66
Pubmed ID
Authors

Nahid Akhtar, Mark JS Miller, Tariq M Haqqi

Abstract

Conventional treatments for the articular diseases are often effective for symptom relief, but can also cause significant side effects and do not slow the progression of the disease. Several natural substances have been shown to be effective at relieving the symptoms of osteoarthritis (OA), and preliminary evidence suggests that some of these compounds may exert a favorable influence on the course of the disease. The objective of this study was to investigate the anti-inflammatory/chondroprotective potential of a Herbal and amino acid mixture containing extract of the Uncaria tomentosa, Boswellia spp., Lepidium meyenii and L-Leucine on the IL-1β-induced production of nitric oxide (NO), glycosaminoglycan (GAG), matrix metalloproteinases (MMPs), aggrecan (ACAN) and type II collagen (COL2A1) in human OA chondrocytes and OA cartilage explants.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 70 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 1%
United States 1 1%
Sweden 1 1%
Brazil 1 1%
Unknown 66 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 14%
Student > Ph. D. Student 9 13%
Student > Master 8 11%
Student > Doctoral Student 8 11%
Student > Bachelor 8 11%
Other 14 20%
Unknown 13 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 18 26%
Medicine and Dentistry 16 23%
Biochemistry, Genetics and Molecular Biology 7 10%
Pharmacology, Toxicology and Pharmaceutical Science 3 4%
Unspecified 2 3%
Other 6 9%
Unknown 18 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 January 2020.
All research outputs
#3,792,308
of 25,393,455 outputs
Outputs from BMC Complementary Medicine and Therapies
#748
of 3,958 outputs
Outputs of similar age
#19,139
of 134,635 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#9
of 29 outputs
Altmetric has tracked 25,393,455 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,958 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.6. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 134,635 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 29 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.