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Candidate genes for male and female reproductive traits in Canchim beef cattle

Overview of attention for article published in Journal of Animal Science and Biotechnology, August 2017
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Title
Candidate genes for male and female reproductive traits in Canchim beef cattle
Published in
Journal of Animal Science and Biotechnology, August 2017
DOI 10.1186/s40104-017-0199-8
Pubmed ID
Authors

Marcos Eli Buzanskas, Daniela do Amaral Grossi, Ricardo Vieira Ventura, Flavio Schramm Schenkel, Tatiane Cristina Seleguim Chud, Nedenia Bonvino Stafuzza, Luciana Diniz Rola, Sarah Laguna Conceição Meirelles, Fabiana Barichello Mokry, Maurício de Alvarenga Mudadu, Roberto Hiroshi Higa, Marcos Vinícius Gualberto Barbosa da Silva, Maurício Mello de Alencar, Luciana Correia de Almeida Regitano, Danísio Prado Munari

Abstract

Beef cattle breeding programs in Brazil have placed greater emphasis on the genomic study of reproductive traits of males and females due to their economic importance. In this study, genome-wide associations were assessed for scrotal circumference at 210 d of age, scrotal circumference at 420 d of age, age at first calving, and age at second calving, in Canchim beef cattle. Data quality control was conducted resulting in 672,778 SNPs and 392 animals. Associated SNPs were observed for scrotal circumference at 420 d of age (435 SNPs), followed by scrotal circumference at 210 d of age (12 SNPs), age at first calving (six SNPs), and age at second calving (four SNPs). We investigated whether significant SNPs were within genic or surrounding regions. Biological processes of genes were associated with immune system, multicellular organismal process, response to stimulus, apoptotic process, cellular component organization or biogenesis, biological adhesion, and reproduction. Few associations were observed for scrotal circumference at 210 d of age, age at first calving, and age at second calving, reinforcing their polygenic inheritance and the complexity of understanding the genetic architecture of reproductive traits. Finding many associations for scrotal circumference at 420 d of age in various regions of the Canchim genome also reveals the difficulty of targeting specific candidate genes that could act on fertility; nonetheless, the high linkage disequilibrium between loci herein estimated could aid to overcome this issue. Therefore, all relevant information about genomic regions influencing reproductive traits may contribute to target candidate genes for further investigation of causal mutations and aid in future genomic studies in Canchim cattle to improve the breeding program.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 67 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 67 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 16%
Student > Ph. D. Student 8 12%
Lecturer 6 9%
Student > Doctoral Student 5 7%
Student > Bachelor 5 7%
Other 16 24%
Unknown 16 24%
Readers by discipline Count As %
Agricultural and Biological Sciences 29 43%
Veterinary Science and Veterinary Medicine 7 10%
Biochemistry, Genetics and Molecular Biology 5 7%
Medicine and Dentistry 2 3%
Business, Management and Accounting 1 1%
Other 3 4%
Unknown 20 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 August 2017.
All research outputs
#17,292,294
of 25,382,440 outputs
Outputs from Journal of Animal Science and Biotechnology
#456
of 904 outputs
Outputs of similar age
#208,341
of 325,032 outputs
Outputs of similar age from Journal of Animal Science and Biotechnology
#8
of 17 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 904 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 325,032 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.