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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Cytotoxicity of VEGF121/rGel on vascular endothelial cells resulting in inhibition of angiogenesis is mediated via VEGFR-2
|
|---|---|
| Published in |
BMC Cancer, August 2011
|
| DOI | 10.1186/1471-2407-11-358 |
| Pubmed ID | |
| Authors |
Khalid A Mohamedali, Sophia Ran, Candelaria Gomez-Manzano, Latha Ramdas, Jing Xu, Sehoon Kim, Lawrence H Cheung, Walter N Hittelman, Wei Zhang, Johannes Waltenberger, Philip E Thorpe, Michael G Rosenblum |
| Abstract |
The fusion protein VEGF(121)/rGel composed of the growth factor VEGF(121) and the plant toxin gelonin targets the tumor neovasculature and exerts impressive anti-vascular effects. We have previously shown that VEGF(121)/rGel is cytotoxic to endothelial cells overexpressing VEGFR-2 but not to endothelial cells overexpressing VEGFR-1. In this study, we examined the basis for the specific toxicity of this construct and assessed its intracellular effects in vitro and in vivo. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 17 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Professor | 3 | 18% |
| Lecturer | 2 | 12% |
| Student > Doctoral Student | 2 | 12% |
| Student > Ph. D. Student | 2 | 12% |
| Student > Bachelor | 1 | 6% |
| Other | 2 | 12% |
| Unknown | 5 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 4 | 24% |
| Agricultural and Biological Sciences | 3 | 18% |
| Medicine and Dentistry | 3 | 18% |
| Neuroscience | 1 | 6% |
| Unknown | 6 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 August 2011.
All research outputs
#20,143,522
of 22,649,029 outputs
Outputs from BMC Cancer
#6,475
of 8,235 outputs
Outputs of similar age
#113,213
of 123,290 outputs
Outputs of similar age from BMC Cancer
#63
of 102 outputs
Altmetric has tracked 22,649,029 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,235 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 123,290 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 102 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.