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Combination treatment with doxorubicin and gamitrinib synergistically augments anticancer activity through enhanced activation of Bim

Overview of attention for article published in BMC Cancer, June 2014
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Title
Combination treatment with doxorubicin and gamitrinib synergistically augments anticancer activity through enhanced activation of Bim
Published in
BMC Cancer, June 2014
DOI 10.1186/1471-2407-14-431
Pubmed ID
Authors

Hye-Kyung Park, Ji-Eun Lee, Jaehwa Lim, Da-Eun Jo, Soo-Ah Park, Pann-Ghill Suh, Byoung Heon Kang

Abstract

A common approach to cancer therapy in clinical practice is the combination of several drugs to boost the anticancer activity of available drugs while suppressing their unwanted side effects. In this regard, we examined the efficacy of combination treatment with the widely-used genotoxic drug doxorubicin and the mitochondriotoxic Hsp90 inhibitor gamitrinib to exploit disparate stress signaling pathways for cancer therapy.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 113 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
Netherlands 1 <1%
United States 1 <1%
Unknown 110 97%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 33 29%
Student > Master 18 16%
Student > Ph. D. Student 11 10%
Student > Postgraduate 9 8%
Researcher 7 6%
Other 17 15%
Unknown 18 16%
Readers by discipline Count As %
Chemistry 16 14%
Engineering 15 13%
Biochemistry, Genetics and Molecular Biology 12 11%
Agricultural and Biological Sciences 10 9%
Medicine and Dentistry 7 6%
Other 30 27%
Unknown 23 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 June 2014.
All research outputs
#18,373,576
of 22,757,090 outputs
Outputs from BMC Cancer
#5,420
of 8,276 outputs
Outputs of similar age
#164,050
of 228,650 outputs
Outputs of similar age from BMC Cancer
#92
of 136 outputs
Altmetric has tracked 22,757,090 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,276 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 228,650 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 136 others from the same source and published within six weeks on either side of this one. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.