Title |
Study of the frequency of Clostridium difficile tcdA, tcdB, cdtA and cdtB genes in feces of Calves in south west of Iran
|
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Published in |
Annals of Clinical Microbiology and Antimicrobials, June 2014
|
DOI | 10.1186/1476-0711-13-21 |
Pubmed ID | |
Authors |
Abbas Doosti, Abbas Mokhtari-Farsani |
Abstract |
Clostridium difficile (C. difficile) is a gram-positive, toxin-producing bacillus which is an intestinal pathogen in both humans and animals and causes a range of digestive disorders including inflammation of the bowel, abdominal pain, fever, and diarrhea. C. difficile toxins include enterotoxin (Toxin A), cytotoxin (Toxin B) and a binary toxin. Two large protein toxins A and B are encoded by separate genes, tcdA and tcdB. Clostridium difficile infection (CDI) mainly caused by the activity of the genes tcdA and tcdB. The binary toxin is encoded by the genes cdtA and cdtB. The binary toxin caused increased adherence of bacteria to intestinal epithelium. The aim of the present study was isolation of C. difficile from feces of calves, and study of the frequency of C. difficile virulence genes. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 49 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 11 | 22% |
Researcher | 6 | 12% |
Student > Bachelor | 4 | 8% |
Professor > Associate Professor | 3 | 6% |
Other | 3 | 6% |
Other | 12 | 24% |
Unknown | 10 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 9 | 18% |
Agricultural and Biological Sciences | 8 | 16% |
Immunology and Microbiology | 8 | 16% |
Medicine and Dentistry | 5 | 10% |
Veterinary Science and Veterinary Medicine | 2 | 4% |
Other | 4 | 8% |
Unknown | 13 | 27% |