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Phenotype prediction based on genome-wide DNA methylation data

Overview of attention for article published in BMC Bioinformatics, June 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (89th percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

Mentioned by

news
1 news outlet
twitter
3 X users
patent
1 patent

Citations

dimensions_citation
22 Dimensions

Readers on

mendeley
71 Mendeley
citeulike
1 CiteULike
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Title
Phenotype prediction based on genome-wide DNA methylation data
Published in
BMC Bioinformatics, June 2014
DOI 10.1186/1471-2105-15-193
Pubmed ID
Authors

Thomas Wilhelm

Abstract

DNA methylation (DNAm) has important regulatory roles in many biological processes and diseases. It is the only epigenetic mark with a clear mechanism of mitotic inheritance and the only one easily available on a genome scale. Aberrant cytosine-phosphate-guanine (CpG) methylation has been discussed in the context of disease aetiology, especially cancer. CpG hypermethylation of promoter regions is often associated with silencing of tumour suppressor genes and hypomethylation with activation of oncogenes.Supervised principal component analysis (SPCA) is a popular machine learning method. However, in a recent application to phenotype prediction from DNAm data SPCA was inferior to the specific method EVORA.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
United States 1 1%
Turkey 1 1%
Unknown 68 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 15 21%
Student > Ph. D. Student 12 17%
Student > Master 10 14%
Student > Bachelor 7 10%
Professor > Associate Professor 6 8%
Other 14 20%
Unknown 7 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 22 31%
Biochemistry, Genetics and Molecular Biology 9 13%
Computer Science 9 13%
Medicine and Dentistry 9 13%
Engineering 2 3%
Other 8 11%
Unknown 12 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 December 2021.
All research outputs
#2,352,478
of 23,881,329 outputs
Outputs from BMC Bioinformatics
#631
of 7,454 outputs
Outputs of similar age
#23,971
of 230,688 outputs
Outputs of similar age from BMC Bioinformatics
#15
of 154 outputs
Altmetric has tracked 23,881,329 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,454 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 230,688 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 154 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.