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Nucleosome organization in the vicinity of transcription factor binding sites in the human genome

Overview of attention for article published in BMC Genomics, June 2014
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Title
Nucleosome organization in the vicinity of transcription factor binding sites in the human genome
Published in
BMC Genomics, June 2014
DOI 10.1186/1471-2164-15-493
Pubmed ID
Authors

Yumin Nie, Xiangfei Cheng, Jiao Chen, Xiao Sun

Abstract

The binding of transcription factors (TFs) to specific DNA sequences is an initial and crucial step of transcription. In eukaryotes, this process is highly dependent on the local chromatin state, which can be modified by recruiting chromatin remodelers. However, previous studies have focused mainly on nucleosome occupancy around the TF binding sites (TFBSs) of a few specific TFs. Here, we investigated the nucleosome occupancy profiles around computationally inferred binding sites, based on 519 TF binding motifs, in human GM12878 and K562 cells.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 2 4%
United States 1 2%
Spain 1 2%
Unknown 44 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 19 40%
Researcher 8 17%
Student > Doctoral Student 3 6%
Other 3 6%
Professor 3 6%
Other 6 13%
Unknown 6 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 21 44%
Biochemistry, Genetics and Molecular Biology 13 27%
Medicine and Dentistry 2 4%
Mathematics 1 2%
Computer Science 1 2%
Other 3 6%
Unknown 7 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 June 2014.
All research outputs
#17,722,431
of 22,757,541 outputs
Outputs from BMC Genomics
#7,548
of 10,637 outputs
Outputs of similar age
#155,696
of 228,247 outputs
Outputs of similar age from BMC Genomics
#123
of 203 outputs
Altmetric has tracked 22,757,541 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 10,637 research outputs from this source. They receive a mean Attention Score of 4.7. This one is in the 23rd percentile – i.e., 23% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 228,247 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 203 others from the same source and published within six weeks on either side of this one. This one is in the 34th percentile – i.e., 34% of its contemporaries scored the same or lower than it.