Title |
Genome-wide identification and functional analysis of Apobec-1-mediated C-to-U RNA editing in mouse small intestine and liver
|
---|---|
Published in |
Genome Biology, June 2014
|
DOI | 10.1186/gb-2014-15-6-r79 |
Pubmed ID | |
Authors |
Valerie Blanc, Eddie Park, Sabine Schaefer, Melanie Miller, Yiing Lin, Susan Kennedy, Anja M Billing, Hisham Ben Hamidane, Johannes Graumann, Ali Mortazavi, Joseph H Nadeau, Nicholas O Davidson |
Abstract |
RNA editing encompasses a post-transcriptional process in which the genomically templated sequence is enzymatically altered and introduces a modified base into the edited transcript. Mammalian C-to-U RNA editing represents a distinct subtype of base modification, whose prototype is intestinal apolipoprotein B mRNA, mediated by the catalytic deaminase Apobec-1. However, the genome-wide identification, tissue-specificity and functional implications of Apobec-1-mediated C-to-U RNA editing remain incompletely explored. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 40% |
Switzerland | 1 | 20% |
United Kingdom | 1 | 20% |
France | 1 | 20% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 40% |
Scientists | 2 | 40% |
Science communicators (journalists, bloggers, editors) | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 2 | 2% |
Unknown | 94 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 19 | 20% |
Researcher | 16 | 17% |
Student > Bachelor | 11 | 11% |
Student > Master | 7 | 7% |
Student > Doctoral Student | 5 | 5% |
Other | 15 | 16% |
Unknown | 23 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 28 | 29% |
Agricultural and Biological Sciences | 27 | 28% |
Medicine and Dentistry | 4 | 4% |
Computer Science | 3 | 3% |
Neuroscience | 3 | 3% |
Other | 7 | 7% |
Unknown | 24 | 25% |