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X Demographics
Mendeley readers
Attention Score in Context
| Title |
RNA biology of disease-associated microsatellite repeat expansions
|
|---|---|
| Published in |
Acta Neuropathologica Communications, August 2017
|
| DOI | 10.1186/s40478-017-0468-y |
| Pubmed ID | |
| Authors |
Kushal J. Rohilla, Keith T. Gagnon |
| Abstract |
Microsatellites, or simple tandem repeat sequences, occur naturally in the human genome and have important roles in genome evolution and function. However, the expansion of microsatellites is associated with over two dozen neurological diseases. A common denominator among the majority of these disorders is the expression of expanded tandem repeat-containing RNA, referred to as xtrRNA in this review, which can mediate molecular disease pathology in multiple ways. This review focuses on the potential impact that simple tandem repeat expansions can have on the biology and metabolism of RNA that contain them and underscores important gaps in understanding. Merging the molecular biology of repeat expansion disorders with the current understanding of RNA biology, including splicing, transcription, transport, turnover and translation, will help clarify mechanisms of disease and improve therapeutic development. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 33% |
| Mexico | 1 | 33% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 143 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 143 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 36 | 25% |
| Student > Bachelor | 22 | 15% |
| Researcher | 16 | 11% |
| Student > Master | 12 | 8% |
| Professor | 7 | 5% |
| Other | 15 | 10% |
| Unknown | 35 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 46 | 32% |
| Agricultural and Biological Sciences | 22 | 15% |
| Medicine and Dentistry | 12 | 8% |
| Neuroscience | 11 | 8% |
| Chemistry | 10 | 7% |
| Other | 6 | 4% |
| Unknown | 36 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 February 2024.
All research outputs
#4,661,498
of 25,366,663 outputs
Outputs from Acta Neuropathologica Communications
#860
of 1,574 outputs
Outputs of similar age
#73,883
of 322,252 outputs
Outputs of similar age from Acta Neuropathologica Communications
#2
of 15 outputs
Altmetric has tracked 25,366,663 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,574 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.7. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 322,252 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.