Title |
The Pseudomonas aeruginosa rhlG and rhlAB genes are inversely regulated and RhlG is not required for rhamnolipid synthesis
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Published in |
BMC Microbiology, June 2014
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DOI | 10.1186/1471-2180-14-160 |
Pubmed ID | |
Authors |
Alexis Bazire, Alain Dufour |
Abstract |
Pseudomonas aeruginosa produces rhamnolipid biosurfactants involved in numerous phenomena including virulence. The transcriptional study of the rhlAB operon encoding two key enzymes for rhamnolipid synthesis led to the discovery of the quorum sensing system RhlRI. The latter positively controls the transcription of rhlAB, as well as of rhlC, which is required for di-rhamnolipid synthesis. The rhlG gene encodes an NADPH-dependent β-ketoacyl reductase. Although it was reported to be required for the biosynthesis of the fatty acid part of rhamnolipids, its function in rhamnolipid synthesis was later questioned. The rhlG transcription and its role in rhamnolipid production were investigated here. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 71 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 13 | 18% |
Student > Ph. D. Student | 12 | 17% |
Student > Bachelor | 10 | 14% |
Student > Doctoral Student | 9 | 13% |
Researcher | 6 | 8% |
Other | 12 | 17% |
Unknown | 9 | 13% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 28 | 39% |
Biochemistry, Genetics and Molecular Biology | 15 | 21% |
Immunology and Microbiology | 8 | 11% |
Environmental Science | 2 | 3% |
Chemical Engineering | 2 | 3% |
Other | 4 | 6% |
Unknown | 12 | 17% |