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Fecal carriage of extended-spectrum β-lactamases and AmpC-producing Escherichia coli in a Libyan community

Overview of attention for article published in Annals of Clinical Microbiology and Antimicrobials, June 2014
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Title
Fecal carriage of extended-spectrum β-lactamases and AmpC-producing Escherichia coli in a Libyan community
Published in
Annals of Clinical Microbiology and Antimicrobials, June 2014
DOI 10.1186/1476-0711-13-22
Pubmed ID
Authors

Salwa Fouad Ahmed, Mostafa Mohamed M Ali, Zienat Kamel Mohamed, Tarek A Moussa, John D Klena

Abstract

Extended-spectrum beta-lactamases (ESBLs), including the AmpC type, are important mechanisms of resistance among Enterobacteriaeceae. CTX-M type extended-spectrum beta- lactamases, of which there are now over 90 variants, are distributed globally, yet appear to vary in regional distribution. AmpC beta-lactamases hydrolyze third generation cephalosporins, but are resistant to inhibition by clavulanate or other beta-lactamase inhibitors in vitro. Fecal carriage and rates of colonization by bacteria harboring these resistance mechanisms have been reported in patients with community-acquired infections and in healthy members of their households. Expression of these ESBLs compromises the efficacy of current antibacterial therapies, potentially increasing the seriousness of hospital- and community-acquired Escherichia coli (E. coli) infections.To investigate the occurrence of ESBL-producing E. coli in human fecal flora isolated from two pediatric populations residing in the Libyan cities Zleiten and Abou El Khoms. Isolates were further studied to characterize genes encoding beta-lactam resistance, and establish genetic relationships.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 118 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 2 2%
France 2 2%
Unknown 114 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 19 16%
Student > Ph. D. Student 15 13%
Researcher 14 12%
Student > Bachelor 11 9%
Student > Postgraduate 11 9%
Other 30 25%
Unknown 18 15%
Readers by discipline Count As %
Medicine and Dentistry 29 25%
Immunology and Microbiology 18 15%
Biochemistry, Genetics and Molecular Biology 14 12%
Agricultural and Biological Sciences 13 11%
Nursing and Health Professions 3 3%
Other 14 12%
Unknown 27 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 June 2014.
All research outputs
#18,373,874
of 22,757,541 outputs
Outputs from Annals of Clinical Microbiology and Antimicrobials
#457
of 606 outputs
Outputs of similar age
#147,843
of 206,472 outputs
Outputs of similar age from Annals of Clinical Microbiology and Antimicrobials
#5
of 9 outputs
Altmetric has tracked 22,757,541 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 606 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one is in the 12th percentile – i.e., 12% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 206,472 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.