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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Alveolar macrophages of GM-CSF knockout mice exhibit mixed M1 and M2 phenotypes
|
|---|---|
| Published in |
BMC Immunology, September 2013
|
| DOI | 10.1186/1471-2172-14-41 |
| Pubmed ID | |
| Authors |
Heidi Dalrymple, Barbara P Barna, Anagha Malur, Achut G Malur, Mani S Kavuru, Mary Jane Thomassen |
| Abstract |
Activin A is a pleiotrophic regulatory cytokine, the ablation of which is neonatal lethal. Healthy human alveolar macrophages (AMs) constitutively express activin A, but AMs of patients with pulmonary alveolar proteinosis (PAP) are deficient in activin A. PAP is an autoimmune lung disease characterized by neutralizing autoantibodies to Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF). Activin A can be stimulated, however, by GM-CSF treatment of AMs in vitro. To further explore pulmonary activin A regulation, we examined AMs in bronchoalveolar lavage (BAL) from wild-type C57BL/6 compared to GM-CSF knockout mice which exhibit a PAP-like histopathology. Both human PAP and mouse GM-CSF knockout AMs are deficient in the transcription factor, peroxisome proliferator activated receptor gamma (PPARγ). |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 4% |
| Japan | 1 | 2% |
| Unknown | 51 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 16 | 30% |
| Researcher | 13 | 24% |
| Student > Doctoral Student | 7 | 13% |
| Student > Master | 5 | 9% |
| Professor | 2 | 4% |
| Other | 5 | 9% |
| Unknown | 6 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 13 | 24% |
| Agricultural and Biological Sciences | 10 | 19% |
| Medicine and Dentistry | 9 | 17% |
| Biochemistry, Genetics and Molecular Biology | 8 | 15% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 6% |
| Other | 2 | 4% |
| Unknown | 9 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 June 2014.
All research outputs
#20,231,820
of 22,757,541 outputs
Outputs from BMC Immunology
#500
of 585 outputs
Outputs of similar age
#176,769
of 201,981 outputs
Outputs of similar age from BMC Immunology
#7
of 9 outputs
Altmetric has tracked 22,757,541 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 585 research outputs from this source. They receive a mean Attention Score of 3.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 201,981 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.