Title |
Furosemide and albumin for diuresis of edema (FADE): a study protocol for a randomized controlled trial
|
---|---|
Published in |
Trials, June 2014
|
DOI | 10.1186/1745-6215-15-222 |
Pubmed ID | |
Authors |
Simon JW Oczkowski, Ian Mazzetti, Maureen O Meade, Cindy Hamielec |
Abstract |
Fluid retention is a common complication of critical illness. It typically results from large-volume fluid infusions during acute resuscitation and is worsened by hypoalbuminemia. Recognized as edema, fluid retention is important for its association with delayed weaning and increased mortality. The standard treatment is the administration of diuretics, with or without albumin. We hypothesize that intravenous 25% albumin plus furosemide, by comparison with furosemide alone, improves diuresis, oxygenation, and hemodynamic stability in the deresuscitation of critically ill, hypoalbuminemic patients. We propose a pilot study to determine the feasibility of a trial to investigate this hypothesis. |
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Geographical breakdown
Country | Count | As % |
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Mexico | 4 | 20% |
Belgium | 2 | 10% |
United States | 1 | 5% |
Colombia | 1 | 5% |
Argentina | 1 | 5% |
Ecuador | 1 | 5% |
Egypt | 1 | 5% |
Canada | 1 | 5% |
Kuwait | 1 | 5% |
Other | 0 | 0% |
Unknown | 7 | 35% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 9 | 45% |
Scientists | 6 | 30% |
Practitioners (doctors, other healthcare professionals) | 4 | 20% |
Science communicators (journalists, bloggers, editors) | 1 | 5% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Australia | 1 | 1% |
Unknown | 82 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Postgraduate | 13 | 16% |
Student > Bachelor | 12 | 14% |
Other | 9 | 11% |
Researcher | 8 | 10% |
Student > Ph. D. Student | 7 | 8% |
Other | 17 | 20% |
Unknown | 17 | 20% |
Readers by discipline | Count | As % |
---|---|---|
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Unknown | 17 | 20% |