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Furosemide and albumin for diuresis of edema (FADE): a study protocol for a randomized controlled trial

Overview of attention for article published in Trials, June 2014
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Title
Furosemide and albumin for diuresis of edema (FADE): a study protocol for a randomized controlled trial
Published in
Trials, June 2014
DOI 10.1186/1745-6215-15-222
Pubmed ID
Authors

Simon JW Oczkowski, Ian Mazzetti, Maureen O Meade, Cindy Hamielec

Abstract

Fluid retention is a common complication of critical illness. It typically results from large-volume fluid infusions during acute resuscitation and is worsened by hypoalbuminemia. Recognized as edema, fluid retention is important for its association with delayed weaning and increased mortality. The standard treatment is the administration of diuretics, with or without albumin. We hypothesize that intravenous 25% albumin plus furosemide, by comparison with furosemide alone, improves diuresis, oxygenation, and hemodynamic stability in the deresuscitation of critically ill, hypoalbuminemic patients. We propose a pilot study to determine the feasibility of a trial to investigate this hypothesis.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 83 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Australia 1 1%
Unknown 82 99%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 13 16%
Student > Bachelor 12 14%
Other 9 11%
Researcher 8 10%
Student > Ph. D. Student 7 8%
Other 17 20%
Unknown 17 20%
Readers by discipline Count As %
Medicine and Dentistry 50 60%
Nursing and Health Professions 4 5%
Pharmacology, Toxicology and Pharmaceutical Science 4 5%
Agricultural and Biological Sciences 3 4%
Business, Management and Accounting 1 1%
Other 4 5%
Unknown 17 20%