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Distinct and overlapping control of 5-methylcytosine and 5-hydroxymethylcytosine by the TET proteins in human cancer cells

Overview of attention for article published in Genome Biology, June 2014
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  • Good Attention Score compared to outputs of the same age (73rd percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

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6 X users
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2 Google+ users

Citations

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95 Dimensions

Readers on

mendeley
148 Mendeley
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2 CiteULike
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Title
Distinct and overlapping control of 5-methylcytosine and 5-hydroxymethylcytosine by the TET proteins in human cancer cells
Published in
Genome Biology, June 2014
DOI 10.1186/gb-2014-15-6-r81
Pubmed ID
Authors

Emily L Putiri, Rochelle L Tiedemann, Joyce J Thompson, Chunsheng Liu, Thai Ho, Jeong-Hyeon Choi, Keith D Robertson

Abstract

The TET family of dioxygenases catalyze conversion of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), but their involvement in establishing normal 5mC patterns during mammalian development and their contributions to aberrant control of 5mC during cellular transformation remain largely unknown. We depleted TET1, TET2, and TET3 in a pluripotent embryonic carcinoma cell model and examined the impact on genome-wide 5mC, 5hmC, and transcriptional patterns.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 148 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Australia 1 <1%
Brazil 1 <1%
South Africa 1 <1%
India 1 <1%
United Kingdom 1 <1%
Belgium 1 <1%
Japan 1 <1%
United States 1 <1%
Unknown 140 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 44 30%
Researcher 30 20%
Student > Master 17 11%
Student > Doctoral Student 9 6%
Student > Bachelor 8 5%
Other 23 16%
Unknown 17 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 58 39%
Biochemistry, Genetics and Molecular Biology 44 30%
Medicine and Dentistry 9 6%
Computer Science 4 3%
Pharmacology, Toxicology and Pharmaceutical Science 3 2%
Other 8 5%
Unknown 22 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 November 2014.
All research outputs
#7,047,002
of 25,373,627 outputs
Outputs from Genome Biology
#3,232
of 4,467 outputs
Outputs of similar age
#63,343
of 243,357 outputs
Outputs of similar age from Genome Biology
#34
of 56 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 4,467 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 243,357 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 56 others from the same source and published within six weeks on either side of this one. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.