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Including non-additive genetic effects in Bayesian methods for the prediction of genetic values based on genome-wide markers

Overview of attention for article published in BMC Genomic Data, August 2011
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Title
Including non-additive genetic effects in Bayesian methods for the prediction of genetic values based on genome-wide markers
Published in
BMC Genomic Data, August 2011
DOI 10.1186/1471-2156-12-74
Pubmed ID
Authors

Dörte Wittenburg, Nina Melzer, Norbert Reinsch

Abstract

Molecular marker information is a common source to draw inferences about the relationship between genetic and phenotypic variation. Genetic effects are often modelled as additively acting marker allele effects. The true mode of biological action can, of course, be different from this plain assumption. One possibility to better understand the genetic architecture of complex traits is to include intra-locus (dominance) and inter-locus (epistasis) interaction of alleles as well as the additive genetic effects when fitting a model to a trait. Several Bayesian MCMC approaches exist for the genome-wide estimation of genetic effects with high accuracy of genetic value prediction. Including pairwise interaction for thousands of loci would probably go beyond the scope of such a sampling algorithm because then millions of effects are to be estimated simultaneously leading to months of computation time. Alternative solving strategies are required when epistasis is studied.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 73 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 3%
Germany 1 1%
Brazil 1 1%
France 1 1%
Argentina 1 1%
Sweden 1 1%
Unknown 66 90%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 23 32%
Researcher 19 26%
Student > Master 6 8%
Student > Bachelor 3 4%
Student > Doctoral Student 3 4%
Other 7 10%
Unknown 12 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 50 68%
Medicine and Dentistry 3 4%
Arts and Humanities 2 3%
Mathematics 2 3%
Biochemistry, Genetics and Molecular Biology 1 1%
Other 2 3%
Unknown 13 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 August 2011.
All research outputs
#17,286,379
of 25,374,647 outputs
Outputs from BMC Genomic Data
#668
of 1,204 outputs
Outputs of similar age
#95,600
of 134,591 outputs
Outputs of similar age from BMC Genomic Data
#6
of 13 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,204 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 34th percentile – i.e., 34% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 134,591 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.