Title |
Carotid intima media thickness is associated with body fat abnormalities in HIV-infected patients
|
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Published in |
BMC Infectious Diseases, June 2014
|
DOI | 10.1186/1471-2334-14-348 |
Pubmed ID | |
Authors |
Paula Freitas, Davide Carvalho, Ana Cristina Santos, António José Madureira, Esteban Martinez, Jorge Pereira, António Sarmento, José Luís Medina |
Abstract |
HIV-infected patients may be at increased risk of cardiovascular (CV) events, and lipodystrophy is generally associated with proatherogenic metabolic disturbances. Carotid intima-media thickness (cIMT) has been used as a surrogate marker for atherosclerosis and it has been shown to be an independent risk factor for CV disease. Our objective was to evaluate cIMT in HIV-infected patients on combined anti-retroviral therapy (cART) with and without lipodystrophy defined by fat mass ratio (L-FMR), and to determine the association of lipodystrophy and visceral obesity [(visceral (VAT), subcutaneous adipose tissue (SAT) volume and VAT/SAT ratio, objectively evaluated by CT scan] with cIMT. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 67% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 45 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 9 | 20% |
Researcher | 7 | 16% |
Student > Bachelor | 5 | 11% |
Student > Ph. D. Student | 3 | 7% |
Professor > Associate Professor | 2 | 4% |
Other | 6 | 13% |
Unknown | 13 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 22 | 49% |
Immunology and Microbiology | 3 | 7% |
Nursing and Health Professions | 2 | 4% |
Biochemistry, Genetics and Molecular Biology | 2 | 4% |
Environmental Science | 1 | 2% |
Other | 1 | 2% |
Unknown | 14 | 31% |