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Hepatic progenitor cells in canine and feline medicine: potential for regenerative strategies

Overview of attention for article published in BMC Veterinary Research, June 2014
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  • Above-average Attention Score compared to outputs of the same age and source (62nd percentile)

Mentioned by

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3 X users

Citations

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9 Dimensions

Readers on

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34 Mendeley
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Title
Hepatic progenitor cells in canine and feline medicine: potential for regenerative strategies
Published in
BMC Veterinary Research, June 2014
DOI 10.1186/1746-6148-10-137
Pubmed ID
Authors

Hedwig S Kruitwagen, Bart Spee, Baukje A Schotanus

Abstract

New curative therapies for severe liver disease are urgently needed in both the human and veterinary clinic. It is important to find new treatment modalities which aim to compensate for the loss of parenchymal tissue and to repopulate the liver with healthy hepatocytes. A prime focus in regenerative medicine of the liver is the use of adult liver stem cells, or hepatic progenitor cells (HPCs), for functional recovery of liver disease. This review describes recent developments in HPC research in dog and cat and compares these findings to experimental rodent studies and human pathology. Specifically, the role of HPCs in liver regeneration, key components of the HPC niche, and HPC activation in specific types of canine and feline liver disease will be reviewed. Finally, the potential applications of HPCs in regenerative medicine of the liver are discussed and a potential role is suggested for dogs as first target species for HPC-based trials.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 34 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 21%
Student > Bachelor 6 18%
Researcher 6 18%
Student > Ph. D. Student 4 12%
Student > Postgraduate 3 9%
Other 3 9%
Unknown 5 15%
Readers by discipline Count As %
Medicine and Dentistry 9 26%
Veterinary Science and Veterinary Medicine 6 18%
Agricultural and Biological Sciences 6 18%
Biochemistry, Genetics and Molecular Biology 4 12%
Engineering 2 6%
Other 1 3%
Unknown 6 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 July 2014.
All research outputs
#15,783,117
of 25,085,910 outputs
Outputs from BMC Veterinary Research
#1,177
of 3,261 outputs
Outputs of similar age
#125,599
of 234,174 outputs
Outputs of similar age from BMC Veterinary Research
#15
of 37 outputs
Altmetric has tracked 25,085,910 research outputs across all sources so far. This one is in the 36th percentile – i.e., 36% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,261 research outputs from this source. They receive a mean Attention Score of 4.2. This one has gotten more attention than average, scoring higher than 63% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 234,174 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 37 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.