Title |
Thermal plasticity of the miRNA transcriptome during Senegalese sole development
|
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Published in |
BMC Genomics, June 2014
|
DOI | 10.1186/1471-2164-15-525 |
Pubmed ID | |
Authors |
Catarina Campos, Arvind YM Sundaram, Luisa MP Valente, Luis EC Conceição, Sofia Engrola, Jorge MO Fernandes |
Abstract |
Several miRNAs are known to control myogenesis in vertebrates. Some of them are specifically expressed in muscle while others have a broader tissue expression but are still involved in establishing the muscle phenotype. In teleosts, water temperature markedly affects embryonic development and larval growth. It has been previously shown that higher embryonic temperatures promoted faster development and increased size of Senegalese sole (Solea senegalensis) larvae relatively to a lower temperature. The role of miRNAs in thermal-plasticity of growth is hitherto unknown. Hence, we have used high-throughput SOLiD sequencing to determine potential changes in the miRNA transcriptome in Senegalese sole embryos that were incubated at 15°C or 21°C until hatching and then reared at a common temperature of 21°C. |
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