@mietek @PowerDNS_Bert @BioNTech_Group @pfizer Synonymous codons are not used at the same frequencies (you'll expect 50/50, 25/25/25/25, 33/33/33, etc). Each organism has a preference for one or two of the options. In humans CCU is prefered over CCA https:
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@chrmosimann @NicolasDenans @james_gagnon Here's a nice paper that talks about some of the implications on codon usage, and providing new codon usage tables (including #zebrafish). https://t.co/R3mrF8cvf6