Title |
Development of an in vitroperiodontal biofilm model for assessing antimicrobial and host modulatory effects of bioactive molecules
|
---|---|
Published in |
BMC Oral Health, June 2014
|
DOI | 10.1186/1472-6831-14-80 |
Pubmed ID | |
Authors |
Emma Millhouse, Anto Jose, Leighann Sherry, David F Lappin, Nisha Patel, Andrew M Middleton, Jonathan Pratten, Shauna Culshaw, Gordon Ramage |
Abstract |
Inflammation within the oral cavity occurs due to dysregulation between microbial biofilms and the host response. Understanding how different oral hygiene products influence inflammatory properties is important for the development of new products. Therefore, creation of a robust host-pathogen biofilm platform capable of evaluating novel oral healthcare compounds is an attractive option. We therefore devised a multi-species biofilm co-culture model to evaluate the naturally derived polyphenol resveratrol (RSV) and gold standard chlorhexidine (CHX) with respect to anti-biofilm and anti-inflammatory properties. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 144 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 28 | 19% |
Student > Master | 24 | 17% |
Researcher | 15 | 10% |
Student > Postgraduate | 14 | 10% |
Student > Bachelor | 9 | 6% |
Other | 19 | 13% |
Unknown | 35 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 41 | 28% |
Immunology and Microbiology | 15 | 10% |
Agricultural and Biological Sciences | 13 | 9% |
Biochemistry, Genetics and Molecular Biology | 11 | 8% |
Pharmacology, Toxicology and Pharmaceutical Science | 7 | 5% |
Other | 18 | 13% |
Unknown | 39 | 27% |