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Distribution of segmental duplications in the context of higher order chromatin organisation of human chromosome 7

Overview of attention for article published in BMC Genomics, June 2014
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Title
Distribution of segmental duplications in the context of higher order chromatin organisation of human chromosome 7
Published in
BMC Genomics, June 2014
DOI 10.1186/1471-2164-15-537
Pubmed ID
Authors

Grit Ebert, Anne Steininger, Robert Weißmann, Vivien Boldt, Allan Lind-Thomsen, Jana Grune, Stefan Badelt, Melanie Heßler, Matthias Peiser, Manuel Hitzler, Lars R Jensen, Ines Müller, Hao Hu, Peter F Arndt, Andreas W Kuss, Katrin Tebel, Reinhard Ullmann

Abstract

Segmental duplications (SDs) are not evenly distributed along chromosomes. The reasons for this biased susceptibility to SD insertion are poorly understood. Accumulation of SDs is associated with increased genomic instability, which can lead to structural variants and genomic disorders such as the Williams-Beuren syndrome. Despite these adverse effects, SDs have become fixed in the human genome. Focusing on chromosome 7, which is particularly rich in interstitial SDs, we have investigated the distribution of SDs in the context of evolution and the three dimensional organisation of the chromosome in order to gain insights into the mutual relationship of SDs and chromatin topology.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 2%
Lithuania 1 2%
United Kingdom 1 2%
Spain 1 2%
Philippines 1 2%
Unknown 36 88%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 22%
Student > Doctoral Student 6 15%
Researcher 6 15%
Student > Master 5 12%
Student > Bachelor 4 10%
Other 7 17%
Unknown 4 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 16 39%
Biochemistry, Genetics and Molecular Biology 13 32%
Medicine and Dentistry 4 10%
Immunology and Microbiology 1 2%
Psychology 1 2%
Other 1 2%
Unknown 5 12%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 June 2014.
All research outputs
#21,264,673
of 23,881,329 outputs
Outputs from BMC Genomics
#9,455
of 10,793 outputs
Outputs of similar age
#196,703
of 229,515 outputs
Outputs of similar age from BMC Genomics
#161
of 201 outputs
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So far Altmetric has tracked 10,793 research outputs from this source. They receive a mean Attention Score of 4.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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