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Mendeley readers
| Title |
Bioinformatic analysis of ciliary transition zone proteins reveals insights into the evolution of ciliopathy networks
|
|---|---|
| Published in |
BMC Genomics, June 2014
|
| DOI | 10.1186/1471-2164-15-531 |
| Pubmed ID | |
| Authors |
Amy R Barker, Karen S Renzaglia, Kimberley Fry, Helen R Dawe |
| Abstract |
Cilia are critical for diverse functions, from motility to signal transduction, and ciliary dysfunction causes inherited diseases termed ciliopathies. Several ciliopathy proteins influence developmental signalling and aberrant signalling explains many ciliopathy phenotypes. Ciliary compartmentalisation is essential for function, and the transition zone (TZ), found at the proximal end of the cilium, has recently emerged as a key player in regulating this process. Ciliary compartmentalisation is linked to two protein complexes, the MKS and NPHP complexes, at the TZ that consist largely of ciliopathy proteins, leading to the hypothesis that ciliopathy proteins affect signalling by regulating ciliary content. However, there is no consensus on complex composition, formation, or the contribution of each component. |
Mendeley readers
The data shown below were compiled from readership statistics for 66 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 1 | 2% |
| Sweden | 1 | 2% |
| India | 1 | 2% |
| United Kingdom | 1 | 2% |
| Taiwan | 1 | 2% |
| Unknown | 61 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 19 | 29% |
| Researcher | 12 | 18% |
| Student > Master | 10 | 15% |
| Student > Bachelor | 8 | 12% |
| Professor | 4 | 6% |
| Other | 4 | 6% |
| Unknown | 9 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 29 | 44% |
| Biochemistry, Genetics and Molecular Biology | 21 | 32% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 2% |
| Nursing and Health Professions | 1 | 2% |
| Veterinary Science and Veterinary Medicine | 1 | 2% |
| Other | 4 | 6% |
| Unknown | 9 | 14% |