Title |
In vitro activity of curcumin in combination with epigallocatechin gallate (EGCG) versus multidrug-resistant Acinetobacter baumannii
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Published in |
BMC Microbiology, June 2014
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DOI | 10.1186/1471-2180-14-172 |
Pubmed ID | |
Authors |
Jonathan W Betts, David W Wareham |
Abstract |
Acinetobacter baumannii is an opportunistic human pathogen often associated with life-threatening infections in the immunocompromised and the critically ill. Strains are often multidrug-resistant (MDR) and due to the lack of new synthetic antimicrobials in development for treatment, attention is increasingly focused on natural compounds either as stand-alone or adjunctive agents. Curcumin (CCM) is a natural polyphenol found in turmeric and isolated from the plant, Curcuma longa. Curcumin has been found to possess many biological properties, including antibacterial activity. In this study the antimicrobial activity of CCM and synergistic effects with epigallocatechin gallate (EGCG) against multidrug-resistant strains of A. baumannii were investigated. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 5 | 28% |
United Kingdom | 3 | 17% |
Mexico | 1 | 6% |
Canada | 1 | 6% |
India | 1 | 6% |
Netherlands | 1 | 6% |
United States | 1 | 6% |
Unknown | 5 | 28% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 13 | 72% |
Practitioners (doctors, other healthcare professionals) | 3 | 17% |
Scientists | 1 | 6% |
Science communicators (journalists, bloggers, editors) | 1 | 6% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 1 | <1% |
Unknown | 114 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 23 | 20% |
Student > Bachelor | 14 | 12% |
Researcher | 13 | 11% |
Student > Master | 8 | 7% |
Lecturer | 6 | 5% |
Other | 19 | 17% |
Unknown | 32 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 21 | 18% |
Biochemistry, Genetics and Molecular Biology | 12 | 10% |
Medicine and Dentistry | 11 | 10% |
Immunology and Microbiology | 9 | 8% |
Chemistry | 9 | 8% |
Other | 18 | 16% |
Unknown | 35 | 30% |