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Processed pseudogene insertions in somatic cells

Overview of attention for article published in Mobile DNA, July 2014
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3 X users

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69 Mendeley
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Title
Processed pseudogene insertions in somatic cells
Published in
Mobile DNA, July 2014
DOI 10.1186/1759-8753-5-20
Pubmed ID
Authors

Haig H Kazazian

Abstract

Processed pseudogenes are copies of messenger RNAs that have been reverse transcribed into DNA and inserted into the genome using the enzymatic activities of active L1 elements. Processed pseudogenes generally lack introns, end in a 3' poly A, and are flanked by target site duplications. Until recently, very few polymorphic processed pseudogenes had been discovered in mammalian genomes. Now several studies have found a number of polymorphic processed pseudogenes in humans. Moreover, processed pseudogenes can occur in somatic cells, including in various cancers and in early fetal development. One recent somatic insertion of a processed pseudogene has caused a Mendelian X-linked disease, chronic granulomatous disease.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 69 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Unknown 68 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 19%
Student > Master 11 16%
Student > Bachelor 8 12%
Professor 6 9%
Researcher 5 7%
Other 10 14%
Unknown 16 23%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 26 38%
Agricultural and Biological Sciences 19 28%
Medicine and Dentistry 6 9%
Computer Science 2 3%
Unknown 16 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 January 2022.
All research outputs
#13,561,111
of 22,986,950 outputs
Outputs from Mobile DNA
#241
of 336 outputs
Outputs of similar age
#111,514
of 228,305 outputs
Outputs of similar age from Mobile DNA
#4
of 7 outputs
Altmetric has tracked 22,986,950 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 336 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.0. This one is in the 26th percentile – i.e., 26% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 228,305 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.