Title |
Docosahexaenoic acid-induced apoptosis is mediated by activation of mitogen-activated protein kinases in human cancer cells
|
---|---|
Published in |
BMC Cancer, July 2014
|
DOI | 10.1186/1471-2407-14-481 |
Pubmed ID | |
Authors |
Soyeon Jeong, Kaipeng Jing, Nayeong Kim, Soyeon Shin, Soyeon Kim, Kyoung-Sub Song, Jun-Young Heo, Ji-Hoon Park, Kang-Sik Seo, Jeongsu Han, Tong Wu, Gi-Ryang Kweon, Seung-Kiel Park, Jong-Il Park, Kyu Lim |
Abstract |
The role of omega-3 polyunsaturated fatty acids (ω3-PUFAs) in cancer prevention has been demonstrated; however, the exact molecular mechanisms underlying the anticancer activity of ω3-PUFAs are not fully understood. Here, we investigated the relationship between the anticancer action of a specific ω3-PUFA docosahexaenoic acid (DHA), and the conventional mitogen-activated protein kinases (MAPKs) including extracellular signal-regulated kinase (ERK), c-JUN N-terminal kinase (JNK) and p38 whose dysregulation has been implicated in human cancers. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 40 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 9 | 23% |
Student > Master | 5 | 13% |
Other | 4 | 10% |
Student > Bachelor | 4 | 10% |
Researcher | 4 | 10% |
Other | 6 | 15% |
Unknown | 8 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 9 | 23% |
Agricultural and Biological Sciences | 5 | 13% |
Nursing and Health Professions | 4 | 10% |
Medicine and Dentistry | 3 | 8% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 5% |
Other | 7 | 18% |
Unknown | 10 | 25% |