Title |
Searching for early breast cancer biomarkers by serum protein profiling of pre-diagnostic serum; a nested case-control study
|
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Published in |
BMC Cancer, August 2011
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DOI | 10.1186/1471-2407-11-381 |
Pubmed ID | |
Authors |
Annemieke WJ Opstal-van Winden, Esmeralda JM Krop, Monica H Kåredal, Marie-Christine W Gast, Christian H Lindh, Marina C Jeppsson, Bo AG Jönsson, Diederick E Grobbee, Petra HM Peeters, Jos H Beijnen, Carla H van Gils, Roel CH Vermeulen |
Abstract |
Serum protein profiles have been investigated frequently to discover early biomarkers for breast cancer. So far, these studies used biological samples collected at or after diagnosis. This may limit these studies' value in the search for cancer biomarkers because of the often advanced tumor stage, and consequently risk of reverse causality. We present for the first time pre-diagnostic serum protein profiles in relation to breast cancer, using the Prospect-EPIC (European Prospective Investigation into Cancer and nutrition) cohort. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 4 | 67% |
Unknown | 2 | 33% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 6 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 2% |
Portugal | 1 | 2% |
Unknown | 56 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 9 | 16% |
Researcher | 8 | 14% |
Student > Master | 6 | 10% |
Professor | 5 | 9% |
Student > Bachelor | 3 | 5% |
Other | 11 | 19% |
Unknown | 16 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 11 | 19% |
Medicine and Dentistry | 7 | 12% |
Biochemistry, Genetics and Molecular Biology | 6 | 10% |
Chemistry | 3 | 5% |
Immunology and Microbiology | 3 | 5% |
Other | 9 | 16% |
Unknown | 19 | 33% |