Title |
Prevalence and distribution of late gadolinium enhancement in a large population of patients with Duchenne muscular dystrophy: effect of age and left ventricular systolic function
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Published in |
Critical Reviews in Diagnostic Imaging, December 2013
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DOI | 10.1186/1532-429x-15-107 |
Pubmed ID | |
Authors |
Kan N Hor, Michael D Taylor, Hussein R Al-Khalidi, Linda H Cripe, Subha V Raman, John L Jefferies, Robert O’Donnell, D Woodrow Benson, Wojciech Mazur |
Abstract |
Duchenne muscular dystrophy (DMD), an X-linked disorder affects approximately 1 in 5000 males, is universally associated with heart disease. We previously identified myocardial disease by late gadolinium enhancement (LGE) in DMD subjects at various stages of disease, but the true prevalence is unclear. Cardiovascular magnetic resonance (CMR) is well established for both assessment of ventricular function and myocardial fibrosis by LGE. We sought to establish i) prevalence and distribution of LGE in a large DMD population and ii) relationship among LGE, age, LVEF by CMR and current living status. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | 1% |
Czechia | 1 | 1% |
Unknown | 93 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 14 | 15% |
Other | 10 | 11% |
Student > Ph. D. Student | 10 | 11% |
Student > Master | 9 | 9% |
Student > Postgraduate | 7 | 7% |
Other | 24 | 25% |
Unknown | 21 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 38 | 40% |
Biochemistry, Genetics and Molecular Biology | 7 | 7% |
Agricultural and Biological Sciences | 7 | 7% |
Engineering | 4 | 4% |
Nursing and Health Professions | 3 | 3% |
Other | 9 | 9% |
Unknown | 27 | 28% |