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Mendeley readers
Attention Score in Context
| Title |
Brain pericytes among cells constituting the blood-brain barrier are highly sensitive to tumor necrosis factor-α, releasing matrix metalloproteinase-9 and migrating in vitro
|
|---|---|
| Published in |
Journal of Neuroinflammation, August 2011
|
| DOI | 10.1186/1742-2094-8-106 |
| Pubmed ID | |
| Authors |
Fuyuko Takata, Shinya Dohgu, Junichi Matsumoto, Hiroyuki Takahashi, Takashi Machida, Tomoya Wakigawa, Eriko Harada, Haruki Miyaji, Mitsuhisa Koga, Tsuyoshi Nishioku, Atsushi Yamauchi, Yasufumi Kataoka |
| Abstract |
Increased matrix metalloproteinase (MMP)-9 in the plasma and brain is associated with blood-brain barrier (BBB) disruption through proteolytic activity in neuroinflammatory diseases. MMP-9 is present in the brain microvasculature and its vicinity, where brain microvascular endothelial cells (BMECs), pericytes and astrocytes constitute the BBB. Little is known about the cellular source and role of MMP-9 at the BBB. Here, we examined the ability of pericytes to release MMP-9 and migrate in response to inflammatory mediators in comparison with BMECs and astrocytes, using primary cultures isolated from rat brains. |
Mendeley readers
The data shown below were compiled from readership statistics for 133 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 2 | 2% |
| Spain | 1 | <1% |
| France | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 128 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 34 | 26% |
| Researcher | 21 | 16% |
| Student > Bachelor | 15 | 11% |
| Student > Master | 13 | 10% |
| Professor | 9 | 7% |
| Other | 26 | 20% |
| Unknown | 15 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 38 | 29% |
| Medicine and Dentistry | 24 | 18% |
| Neuroscience | 24 | 18% |
| Biochemistry, Genetics and Molecular Biology | 10 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 5% |
| Other | 14 | 11% |
| Unknown | 17 | 13% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 August 2011.
All research outputs
#20,145,561
of 22,651,245 outputs
Outputs from Journal of Neuroinflammation
#2,281
of 2,601 outputs
Outputs of similar age
#113,898
of 124,037 outputs
Outputs of similar age from Journal of Neuroinflammation
#10
of 13 outputs
Altmetric has tracked 22,651,245 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,601 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 124,037 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.