Title |
Amygdala opioid receptors mediate the electroacupuncture-induced deterioration of sleep disruptions in epilepsy rats
|
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Published in |
Journal of Biomedical Science, November 2013
|
DOI | 10.1186/1423-0127-20-85 |
Pubmed ID | |
Authors |
Pei-Lu Yi, Chin-Yu Lu, Chiung-Hsiang Cheng, Yi-Fong Tsai, Chung-Tien Lin, Fang-Chia Chang |
Abstract |
Clinical and experimental evidence demonstrates that sleep and epilepsy reciprocally affect each other. Previous studies indicated that epilepsy alters sleep homeostasis; in contrast, sleep disturbance deteriorates epilepsy. If a therapy possesses both epilepsy suppression and sleep improvement, it would be the priority choice for seizure control. Effects of acupuncture of Feng-Chi (GB20) acupoints on epilepsy suppression and insomnia treatment have been documented in the ancient Chinese literature, Lingshu Jing (Classic of the Miraculous Pivot). Therefore, this study was designed to investigate the effect of electroacupuncture (EA) stimulation of bilateral Feng-Chi acupoints on sleep disruptions in rats with focal epilepsy. |
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