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Combined use of ursodeoxycholic acid and bosentan prevents liver toxicity caused by endothelin receptor antagonist bosentan monotherapy: two case reports

Overview of attention for article published in Journal of Medical Case Reports, July 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (87th percentile)

Mentioned by

news
1 news outlet
twitter
3 tweeters

Citations

dimensions_citation
7 Dimensions

Readers on

mendeley
17 Mendeley
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Title
Combined use of ursodeoxycholic acid and bosentan prevents liver toxicity caused by endothelin receptor antagonist bosentan monotherapy: two case reports
Published in
Journal of Medical Case Reports, July 2014
DOI 10.1186/1752-1947-8-250
Pubmed ID
Authors

Tomoki Ito, Yoshio Ozaki, Yonsu Son, Tohru Nishizawa, Hideki Amuro, Akihiro Tanaka, Takeshi Tamaki, Shosaku Nomura

Abstract

Pulmonary arterial hypertension is a fatal disease characterized by progressive remodeling of the pulmonary arteries and an increase in pulmonary vascular resistance. Up to 50% of patients with systemic sclerosis have pulmonary arterial hypertension, which significantly affects the prognosis. The endothelin receptor antagonist bosentan is used for the treatment of pulmonary arterial hypertension and shows a great beneficial effect. However, the most frequent side effect of bosentan is liver toxicity, which often requires dose reduction and discontinuation.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 17 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 29%
Student > Bachelor 3 18%
Other 2 12%
Student > Doctoral Student 1 6%
Researcher 1 6%
Other 1 6%
Unknown 4 24%
Readers by discipline Count As %
Medicine and Dentistry 13 76%
Biochemistry, Genetics and Molecular Biology 1 6%
Nursing and Health Professions 1 6%
Engineering 1 6%
Unknown 1 6%

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 April 2015.
All research outputs
#2,390,821
of 21,343,037 outputs
Outputs from Journal of Medical Case Reports
#173
of 3,635 outputs
Outputs of similar age
#24,321
of 202,727 outputs
Outputs of similar age from Journal of Medical Case Reports
#1
of 1 outputs
Altmetric has tracked 21,343,037 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,635 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 202,727 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them