Title |
Corticosteroid treatment for community-acquired pneumonia - the STEP trial: study protocol for a randomized controlled trial
|
---|---|
Published in |
Trials, June 2014
|
DOI | 10.1186/1745-6215-15-257 |
Pubmed ID | |
Authors |
Claudine A Blum, Nicole Nigro, Bettina Winzeler, Isabelle Suter-Widmer, Philipp Schuetz, Matthias Briel, Roland Bingisser, Werner Zimmerli, Elke Ullmer, Hanno Elsaesser, Philip Tarr, Sebastian Wirz, Robert Thomann, Eveline Hofmann, Nicolas Rodondi, Hervé Duplain, Dieter Burki, Beat Mueller, Mirjam Christ-Crain |
Abstract |
Community-acquired pneumonia (CAP) is the third-leading infectious cause of death worldwide. The standard treatment of CAP has not changed for the past fifty years and its mortality and morbidity remain high despite adequate antimicrobial treatment. Systemic corticosteroids have anti-inflammatory effects and are therefore discussed as adjunct treatment for CAP. Available studies show controversial results, and the question about benefits and harms of adjunct corticosteroid therapy has not been conclusively resolved, particularly in the non-critical care setting. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 1 | 14% |
United States | 1 | 14% |
United Kingdom | 1 | 14% |
Unknown | 4 | 57% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 43% |
Practitioners (doctors, other healthcare professionals) | 2 | 29% |
Scientists | 1 | 14% |
Science communicators (journalists, bloggers, editors) | 1 | 14% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | <1% |
Unknown | 113 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 20 | 18% |
Researcher | 19 | 17% |
Student > Bachelor | 13 | 11% |
Other | 12 | 11% |
Student > Doctoral Student | 9 | 8% |
Other | 20 | 18% |
Unknown | 21 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 60 | 53% |
Nursing and Health Professions | 6 | 5% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 4% |
Agricultural and Biological Sciences | 4 | 4% |
Engineering | 3 | 3% |
Other | 12 | 11% |
Unknown | 24 | 21% |