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Corticosteroid treatment for community-acquired pneumonia - the STEP trial: study protocol for a randomized controlled trial

Overview of attention for article published in Trials, June 2014
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Title
Corticosteroid treatment for community-acquired pneumonia - the STEP trial: study protocol for a randomized controlled trial
Published in
Trials, June 2014
DOI 10.1186/1745-6215-15-257
Pubmed ID
Authors

Claudine A Blum, Nicole Nigro, Bettina Winzeler, Isabelle Suter-Widmer, Philipp Schuetz, Matthias Briel, Roland Bingisser, Werner Zimmerli, Elke Ullmer, Hanno Elsaesser, Philip Tarr, Sebastian Wirz, Robert Thomann, Eveline Hofmann, Nicolas Rodondi, Hervé Duplain, Dieter Burki, Beat Mueller, Mirjam Christ-Crain

Abstract

Community-acquired pneumonia (CAP) is the third-leading infectious cause of death worldwide. The standard treatment of CAP has not changed for the past fifty years and its mortality and morbidity remain high despite adequate antimicrobial treatment. Systemic corticosteroids have anti-inflammatory effects and are therefore discussed as adjunct treatment for CAP. Available studies show controversial results, and the question about benefits and harms of adjunct corticosteroid therapy has not been conclusively resolved, particularly in the non-critical care setting.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 114 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
Unknown 113 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 20 18%
Researcher 19 17%
Student > Bachelor 13 11%
Other 12 11%
Student > Doctoral Student 9 8%
Other 20 18%
Unknown 21 18%
Readers by discipline Count As %
Medicine and Dentistry 60 53%
Nursing and Health Professions 6 5%
Pharmacology, Toxicology and Pharmaceutical Science 5 4%
Agricultural and Biological Sciences 4 4%
Engineering 3 3%
Other 12 11%
Unknown 24 21%