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Transcriptomic analysis of the zebrafish inner ear points to growth hormone mediated regeneration following acoustic trauma

Overview of attention for article published in BMC Neuroscience, September 2011
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Title
Transcriptomic analysis of the zebrafish inner ear points to growth hormone mediated regeneration following acoustic trauma
Published in
BMC Neuroscience, September 2011
DOI 10.1186/1471-2202-12-88
Pubmed ID
Authors

Julie B Schuck, Huifang Sun, W Todd Penberthy, Nigel GF Cooper, Xiaohong Li, Michael E Smith

Abstract

Unlike mammals, teleost fishes are capable of regenerating sensory inner ear hair cells that have been lost following acoustic or ototoxic trauma. Previous work indicated that immediately following sound exposure, zebrafish saccules exhibit significant hair cell loss that recovers to pre-treatment levels within 14 days. Following acoustic trauma in the zebrafish inner ear, we used microarray analysis to identify genes involved in inner ear repair following acoustic exposure. Additionally, we investigated the effect of growth hormone (GH) on cell proliferation in control zebrafish utricles and saccules, since GH was significantly up-regulated following acoustic trauma.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 2 3%
Germany 1 2%
Netherlands 1 2%
Spain 1 2%
United States 1 2%
Unknown 57 90%

Demographic breakdown

Readers by professional status Count As %
Researcher 14 22%
Student > Ph. D. Student 13 21%
Student > Bachelor 8 13%
Professor > Associate Professor 7 11%
Student > Master 6 10%
Other 9 14%
Unknown 6 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 22 35%
Biochemistry, Genetics and Molecular Biology 10 16%
Medicine and Dentistry 8 13%
Neuroscience 4 6%
Environmental Science 3 5%
Other 6 10%
Unknown 10 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 March 2012.
All research outputs
#19,292,491
of 23,881,329 outputs
Outputs from BMC Neuroscience
#898
of 1,265 outputs
Outputs of similar age
#105,226
of 127,139 outputs
Outputs of similar age from BMC Neuroscience
#14
of 17 outputs
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