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Synergistic anticancer effects of a bioactive subfraction of Strobilanthes crispus and tamoxifen on MCF-7 and MDA-MB-231 human breast cancer cell lines

Overview of attention for article published in BMC Complementary Medicine and Therapies, July 2014
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  • Above-average Attention Score compared to outputs of the same age and source (61st percentile)

Mentioned by

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3 X users

Citations

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39 Dimensions

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85 Mendeley
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Title
Synergistic anticancer effects of a bioactive subfraction of Strobilanthes crispus and tamoxifen on MCF-7 and MDA-MB-231 human breast cancer cell lines
Published in
BMC Complementary Medicine and Therapies, July 2014
DOI 10.1186/1472-6882-14-252
Pubmed ID
Authors

Nik Soriani Yaacob, Nik Nursyazni Nik Mohamed Kamal, Mohd Nor Norazmi

Abstract

Development of tumour resistance to chemotherapeutic drugs and concerns over their toxic effects has led to the increased use of medicinal herbs or natural products by cancer patients. Strobilanthes crispus is a traditional remedy for many ailments including cancer. Its purported anticancer effects have led to the commercialization of the plant leaves as medicinal herbal tea, although the scientific basis for its use has not been established. We previously reported that a bioactive subfraction of Strobilanthes crispus leaves (SCS) exhibit potent cytotoxic activity against human breast cancer cell lines. The current study investigates the effect of this subfraction on cell death activities induced by the antiestrogen drug, tamoxifen, in estrogen receptor-responsive and nonresponsive breast cancer cells.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 85 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 85 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 16 19%
Student > Master 13 15%
Researcher 11 13%
Student > Ph. D. Student 8 9%
Professor > Associate Professor 3 4%
Other 9 11%
Unknown 25 29%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 18%
Biochemistry, Genetics and Molecular Biology 12 14%
Pharmacology, Toxicology and Pharmaceutical Science 9 11%
Chemistry 5 6%
Medicine and Dentistry 5 6%
Other 9 11%
Unknown 30 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 March 2015.
All research outputs
#13,410,616
of 22,758,963 outputs
Outputs from BMC Complementary Medicine and Therapies
#1,502
of 3,621 outputs
Outputs of similar age
#109,147
of 228,762 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#38
of 104 outputs
Altmetric has tracked 22,758,963 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,621 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.5. This one has gotten more attention than average, scoring higher than 56% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 228,762 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.
We're also able to compare this research output to 104 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.