Title |
Increase in the prevalence of hypertension among adults exposed to the Great Chinese Famine during early life
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Published in |
Environmental Health and Preventive Medicine, August 2017
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DOI | 10.1186/s12199-017-0671-2 |
Pubmed ID | |
Authors |
Lingli Liu, Xianglong Xu, Huan Zeng, Yong Zhang, Zumin Shi, Fan Zhang, Xianqing Cao, Yao Jie Xie, Cesar Reis, Yong Zhao |
Abstract |
This study aimed to assess the association between exposure to the Great Chinese Famine (1959-1961) during early life and hypertension in adulthood. From July to September 2009, 1224 eligible adults were recruited in a cross-sectional survey using a multi-stage stratified random sampling method in Chongqing China. A questionnaire was used to collect information of hypertension and sociodemographic factors. Participants were categorized as childhood, fetal, and none exposure to famine based on the date of birth. Of the sample, 12.3% reported having hypertension. The prevalence of hypertension varied by famine status: 11.9% in childhood exposure, 16.1% in fetal exposure, and 10.2% in non-exposure group. After adjusting for sociodemographic and lifestyle factors, compared with non-exposure group, fetal exposure group had an increased likelihood of having hypertension with odds ratio of 1.79 (95%CI 1.13-2.84). Although there was no significant gender and famine interaction, the positive association between famine exposure and hypertension was stronger among women than men. Fetal exposure to the Chinese famine may be associated with an increased risk of arthritis in adulthood in women. |
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Geographical breakdown
Country | Count | As % |
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Unknown | 54 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 8 | 15% |
Student > Bachelor | 6 | 11% |
Student > Ph. D. Student | 4 | 7% |
Student > Doctoral Student | 3 | 6% |
Student > Postgraduate | 3 | 6% |
Other | 5 | 9% |
Unknown | 25 | 46% |
Readers by discipline | Count | As % |
---|---|---|
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Biochemistry, Genetics and Molecular Biology | 7 | 13% |
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Agricultural and Biological Sciences | 3 | 6% |
Business, Management and Accounting | 1 | 2% |
Other | 5 | 9% |
Unknown | 25 | 46% |