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Computational reconstruction of proteome-wide protein interaction networks between HTLV retroviruses and Homo sapiens

Overview of attention for article published in BMC Bioinformatics, July 2014
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Title
Computational reconstruction of proteome-wide protein interaction networks between HTLV retroviruses and Homo sapiens
Published in
BMC Bioinformatics, July 2014
DOI 10.1186/1471-2105-15-245
Pubmed ID
Authors

Suyu Mei, Hao Zhu

Abstract

Human T-cell leukemia viruses (HTLV) tend to induce some fatal human diseases like Adult T-cell Leukemia (ATL) by targeting human T lymphocytes. To indentify the protein-protein interactions (PPI) between HTLV viruses and Homo sapiens is one of the significant approaches to reveal the underlying mechanism of HTLV infection and host defence. At present, as biological experiments are labor-intensive and expensive, the identified part of the HTLV-human PPI networks is rather small. Although recent years have witnessed much progress in computational modeling for reconstructing pathogen-host PPI networks, data scarcity and data unavailability are two major challenges to be effectively addressed. To our knowledge, no computational method for proteome-wide HTLV-human PPI networks reconstruction has been reported.

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X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 1 4%
Brazil 1 4%
Unknown 24 92%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 19%
Student > Ph. D. Student 5 19%
Student > Master 3 12%
Other 2 8%
Student > Postgraduate 2 8%
Other 5 19%
Unknown 4 15%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 7 27%
Agricultural and Biological Sciences 5 19%
Computer Science 5 19%
Medicine and Dentistry 2 8%
Neuroscience 1 4%
Other 0 0%
Unknown 6 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 October 2014.
All research outputs
#13,715,377
of 22,758,963 outputs
Outputs from BMC Bioinformatics
#4,440
of 7,272 outputs
Outputs of similar age
#112,744
of 228,762 outputs
Outputs of similar age from BMC Bioinformatics
#76
of 132 outputs
Altmetric has tracked 22,758,963 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,272 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one is in the 38th percentile – i.e., 38% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 228,762 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 132 others from the same source and published within six weeks on either side of this one. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.