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Mendeley readers
Attention Score in Context
| Title |
Cerebrolysin™ efficacy in a transgenic model of tauopathy: role in regulation of mitochondrial structure
|
|---|---|
| Published in |
BMC Neuroscience, July 2014
|
| DOI | 10.1186/1471-2202-15-90 |
| Pubmed ID | |
| Authors |
Edward Rockenstein, Kiren Ubhi, Margarita Trejo, Michael Mante, Christina Patrick, Anthony Adame, Philipp Novak, Marion Jech, Edith Doppler, Herbert Moessler, Eliezer Masliah |
| Abstract |
Alzheimer's Disease (AD) and Fronto temporal lobar dementia (FTLD) are common causes of dementia in the aging population for which limited therapeutical options are available. These disorders are associated with Tau accumulation. We have previously shown that Cerebrolysin™ (CBL), a neuropeptide mixture with neurotrophic effects, ameliorates the behavioral deficits and neuropathological alterations in amyloid precursor protein (APP) transgenic (tg) mouse model of AD by reducing hyper-phosphorylated Tau. CBL has been tested in clinical trials for AD, however it's potential beneficial effects in FTLD are unknown. For this purpose we sought to investigate the effects of CBL in a tg model of tauopathy. Accordingly, double tg mice expressing mutant Tau under the mThy-1 promoter and GSK3β (to enhance Tau phosphorylation) were treated with CBL and evaluated neuropathologically. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 16 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Postgraduate | 3 | 19% |
| Researcher | 3 | 19% |
| Student > Master | 2 | 13% |
| Student > Ph. D. Student | 1 | 6% |
| Student > Doctoral Student | 1 | 6% |
| Other | 1 | 6% |
| Unknown | 5 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 2 | 13% |
| Neuroscience | 2 | 13% |
| Medicine and Dentistry | 2 | 13% |
| Biochemistry, Genetics and Molecular Biology | 1 | 6% |
| Psychology | 1 | 6% |
| Other | 3 | 19% |
| Unknown | 5 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 January 2020.
All research outputs
#15,303,056
of 22,758,963 outputs
Outputs from BMC Neuroscience
#704
of 1,242 outputs
Outputs of similar age
#132,197
of 228,570 outputs
Outputs of similar age from BMC Neuroscience
#19
of 34 outputs
Altmetric has tracked 22,758,963 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,242 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 34th percentile – i.e., 34% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 228,570 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 34 others from the same source and published within six weeks on either side of this one. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.