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Nicotine patch preloading for smoking cessation (the preloading trial): study protocol for a randomized controlled trial

Overview of attention for article published in Trials, July 2014
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Title
Nicotine patch preloading for smoking cessation (the preloading trial): study protocol for a randomized controlled trial
Published in
Trials, July 2014
DOI 10.1186/1745-6215-15-296
Pubmed ID
Authors

Nicola Lindson-Hawley, Tim Coleman, Graeme Docherty, Peter Hajek, Sarah Lewis, Deborah Lycett, Andy McEwen, Hayden McRobbie, Marcus R Munafò, Steve Parrott, Paul Aveyard

Abstract

The use of nicotine replacement therapy before quitting smoking is called nicotine preloading. Standard smoking cessation protocols suggest commencing nicotine replacement therapy only on the first day of quitting smoking (quit day) aiming to reduce withdrawal symptoms and craving. However, other, more successful smoking cessation pharmacotherapies are used prior to the quit day as well as after. Nicotine preloading could improve quit rates by reducing satisfaction from smoking prior to quitting and breaking the association between smoking and reward. A systematic literature review suggests that evidence for the effectiveness of preloading is inconclusive and further trials are needed.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 67 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Denmark 1 1%
Unknown 66 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 15%
Student > Master 9 13%
Student > Ph. D. Student 6 9%
Student > Bachelor 4 6%
Professor > Associate Professor 4 6%
Other 10 15%
Unknown 24 36%
Readers by discipline Count As %
Medicine and Dentistry 12 18%
Psychology 6 9%
Social Sciences 5 7%
Nursing and Health Professions 4 6%
Agricultural and Biological Sciences 3 4%
Other 10 15%
Unknown 27 40%