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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The structural network of Interleukin-10 and its implications in inflammation and cancer
|
|---|---|
| Published in |
BMC Genomics, May 2014
|
| DOI | 10.1186/1471-2164-15-s4-s2 |
| Pubmed ID | |
| Authors |
Ece Saliha Acuner-Ozbabacan, Billur Hatice Engin, Emine Guven-Maiorov, Guray Kuzu, Serena Muratcioglu, Alper Baspinar, Zhong Chen, Carter Van Waes, Attila Gursoy, Ozlem Keskin, Ruth Nussinov |
| Abstract |
Inflammation has significant roles in all phases of tumor development, including initiation, progression and metastasis. Interleukin-10 (IL-10) is a well-known immuno-modulatory cytokine with an anti-inflammatory activity. Lack of IL-10 allows induction of pro-inflammatory cytokines and hinders anti-tumor immunity, thereby favoring tumor growth. The IL-10 network is among the most important paths linking cancer and inflammation. The simple node-and-edge network representation is useful, but limited, hampering the understanding of the mechanistic details of signaling pathways. Structural networks complete the missing parts, and provide details. The IL-10 structural network may shed light on the mechanisms through which disease-related mutations work and the pathogenesis of malignancies. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 69 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 1% |
| Spain | 1 | 1% |
| Unknown | 67 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 15 | 22% |
| Researcher | 13 | 19% |
| Student > Bachelor | 6 | 9% |
| Student > Postgraduate | 5 | 7% |
| Professor | 4 | 6% |
| Other | 14 | 20% |
| Unknown | 12 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 16 | 23% |
| Medicine and Dentistry | 14 | 20% |
| Agricultural and Biological Sciences | 11 | 16% |
| Computer Science | 5 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
| Other | 6 | 9% |
| Unknown | 15 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 July 2014.
All research outputs
#20,233,066
of 22,758,963 outputs
Outputs from BMC Genomics
#9,263
of 10,637 outputs
Outputs of similar age
#191,907
of 226,283 outputs
Outputs of similar age from BMC Genomics
#158
of 197 outputs
Altmetric has tracked 22,758,963 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 10,637 research outputs from this source. They receive a mean Attention Score of 4.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,283 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 197 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.