Title |
Dysautonomia, fibromyalgia and reflex dystrophy
|
---|---|
Published in |
Arthritis Research & Therapy, July 2007
|
DOI | 10.1186/ar2212 |
Pubmed ID | |
Authors |
Jean Eisinger |
Abstract |
Autonomic nervous system dysfunction observed in fibromyalgia, characterized without exception by a sympathetic hyperactivity and hyporeactivity, has been reported. However, several studies demonstrated reduced levels of norepinephrine and neuropeptide Y at rest and after tilt table in some patients, which was improved by beta-stimulating agents. These findings support heterogeneity in fibromyalgia-associated dysautonomia. Fibromyalgia could be a generalized sympathetic dystrophy since both conditions are activated by trauma and partly linked to sympathetic mechanisms. Yet they differ on several points: hormonal and neurochemical abnormalities are observed in fibromyalgia whereas activation by peripheral trauma and hyperosteolysis are observed in reflex sympathetic dystrophy. |
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Geographical breakdown
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Spain | 1 | 3% |
United States | 1 | 3% |
Brazil | 1 | 3% |
Unknown | 30 | 88% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Unspecified | 7 | 21% |
Student > Master | 5 | 15% |
Other | 5 | 15% |
Researcher | 4 | 12% |
Student > Postgraduate | 3 | 9% |
Other | 8 | 24% |
Unknown | 2 | 6% |
Readers by discipline | Count | As % |
---|---|---|
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Unspecified | 7 | 21% |
Psychology | 5 | 15% |
Nursing and Health Professions | 4 | 12% |
Agricultural and Biological Sciences | 2 | 6% |
Other | 3 | 9% |
Unknown | 4 | 12% |