Title |
Biology and therapy of fibromyalgia. Evidence-based biomarkers for fibromyalgia syndrome
|
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Published in |
Arthritis Research & Therapy, August 2008
|
DOI | 10.1186/ar2443 |
Pubmed ID | |
Authors |
Dina Dadabhoy, Leslie J Crofford, Michael Spaeth, I Jon Russell, Daniel J Clauw |
Abstract |
Researchers studying fibromyalgia strive to identify objective, measurable biomarkers that may identify susceptible individuals, may facilitate diagnosis, or that parallel activity of the disease. Candidate objective measures range from sophisticated functional neuroimaging to office-ready measures of the pressure pain threshold. A systematic literature review was completed to assess highly investigated, objective measures used in fibromyalgia studies. To date, only experimental pain testing has been shown to coincide with improvements in clinical status in a longitudinal study. Concerted efforts to systematically evaluate additional objective measures in research trials will be vital for ongoing progress in outcome research and translation into clinical practice. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Israel | 3 | 1% |
Spain | 3 | 1% |
Italy | 2 | <1% |
United States | 2 | <1% |
Brazil | 1 | <1% |
Australia | 1 | <1% |
Portugal | 1 | <1% |
Unknown | 199 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 28 | 13% |
Student > Master | 26 | 12% |
Student > Doctoral Student | 24 | 11% |
Student > Bachelor | 22 | 10% |
Student > Ph. D. Student | 19 | 9% |
Other | 60 | 28% |
Unknown | 33 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 68 | 32% |
Agricultural and Biological Sciences | 21 | 10% |
Psychology | 20 | 9% |
Nursing and Health Professions | 17 | 8% |
Neuroscience | 9 | 4% |
Other | 37 | 17% |
Unknown | 40 | 19% |