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Microarray analysis reveals global modulation of endogenous retroelement transcription by microbes

Overview of attention for article published in Retrovirology, July 2014
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (53rd percentile)
  • Good Attention Score compared to outputs of the same age and source (75th percentile)

Mentioned by

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5 X users
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1 Google+ user

Citations

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46 Dimensions

Readers on

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86 Mendeley
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2 CiteULike
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Title
Microarray analysis reveals global modulation of endogenous retroelement transcription by microbes
Published in
Retrovirology, July 2014
DOI 10.1186/1742-4690-11-59
Pubmed ID
Authors

George R Young, Bettina Mavrommatis, George Kassiotis

Abstract

A substantial proportion of both the mouse and human genomes comprise of endogenous retroelements (REs), which include endogenous retroviruses. Over evolutionary time, REs accumulate inactivating mutations or deletions and thus lose the ability to replicate. Additionally, REs can be transcriptionally repressed by dedicated mechanisms of the host. Nevertheless, many of them still possess and express intact open reading frames, and their transcriptional activity has been associated with many physiological and pathological processes of the host. However, this association remains tenuous due to incomplete understanding of the mechanism by which RE transcription is regulated. Here, we use a bioinformatics tool to examine RE transcriptional activity, measured by microarrays, in murine and human immune cells responding to microbial stimulation.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 86 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Iran, Islamic Republic of 1 1%
Germany 1 1%
Canada 1 1%
Unknown 83 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 20 23%
Researcher 16 19%
Student > Master 8 9%
Student > Doctoral Student 7 8%
Student > Bachelor 6 7%
Other 13 15%
Unknown 16 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 30 35%
Biochemistry, Genetics and Molecular Biology 19 22%
Immunology and Microbiology 11 13%
Medicine and Dentistry 8 9%
Environmental Science 1 1%
Other 1 1%
Unknown 16 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 November 2014.
All research outputs
#8,647,454
of 25,654,806 outputs
Outputs from Retrovirology
#459
of 1,275 outputs
Outputs of similar age
#79,522
of 240,648 outputs
Outputs of similar age from Retrovirology
#5
of 20 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,275 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one has gotten more attention than average, scoring higher than 53% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 240,648 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.