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Cesarean section to prevent mother-to-child transmission of hepatitis B virus in China: A meta-analysis

Overview of attention for article published in BMC Pregnancy and Childbirth, September 2017
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  • Above-average Attention Score compared to outputs of the same age and source (60th percentile)

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Title
Cesarean section to prevent mother-to-child transmission of hepatitis B virus in China: A meta-analysis
Published in
BMC Pregnancy and Childbirth, September 2017
DOI 10.1186/s12884-017-1487-1
Pubmed ID
Authors

Mei Yang, Qin Qin, Qiong Fang, Lixin Jiang, Shaofa Nie

Abstract

Hepatitis B virus (HBV) is predominantly transmitted through mother-to-child transmission (MTCT). To date, it remains unclear whether the method of parturition affects MTCT of HBV. In order to clarify whether cesarean section, when compared with vaginal delivery, could reduce the risk of MTCT of HBV in China, we conducted this meta-analysis. A systematic literature search was performed of the PubMed (Medline), Embase, ISI Web of Science, China Biological Medicine Database, China National Knowledge Infrastructure, and VIP Database for Chinese Technical Periodicals databases for articles written in English or Chinese through July 2015.The reference lists of relevant articles were also scrutinized for additional papers. Randomized controlled trials, cohort studies, or case-control studies investigating the effect of delivery mode on MTCT of HBV were included. This analysis involved 28 articles containing 30 datasets. The data encompassed 9906 participants. The MTCT rate of HBV was 6.76% (670 of 9906) overall, with individual rates of 4.37% (223 of 5105) for mothers who underwent cesarean section and 9.31% (447 of 4801) for those who underwent vaginal delivery. The summary relative risk (RR) was 0.51 (95%CI: 0.44-0.60, P < 0.001), indicating a statistically significant decrease in HBV vertical transmission via cesarean section compared with vaginal delivery. The heterogeneity among studies was moderate with an I (2) of29.3%.Publication bias was not detected by the Egger's and Begg's tests, and the funnel plot was symmetric. In the subgroup analyses, maternal hepatitis B e antigen status and follow-up time did not affect the significance of the results, but hepatitis B immune globulin (HBIG) administration to mother and infant did. Cesarean section could reduce the risk of MTCT of HBV in comparison to vaginal delivery in China. However, owing to several limitations of our meta-analysis, future well-designed randomized controlled trials with adequate statistical power, might be a more appropriate next step.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 96 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 96 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 16 17%
Student > Postgraduate 9 9%
Student > Bachelor 9 9%
Researcher 8 8%
Other 7 7%
Other 9 9%
Unknown 38 40%
Readers by discipline Count As %
Medicine and Dentistry 30 31%
Nursing and Health Professions 10 10%
Biochemistry, Genetics and Molecular Biology 4 4%
Economics, Econometrics and Finance 3 3%
Immunology and Microbiology 2 2%
Other 4 4%
Unknown 43 45%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 December 2020.
All research outputs
#5,780,788
of 23,002,898 outputs
Outputs from BMC Pregnancy and Childbirth
#1,487
of 4,234 outputs
Outputs of similar age
#90,811
of 316,004 outputs
Outputs of similar age from BMC Pregnancy and Childbirth
#32
of 80 outputs
Altmetric has tracked 23,002,898 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 4,234 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.9. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 316,004 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 80 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.