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Validation and assessment of variant calling pipelines for next-generation sequencing

Overview of attention for article published in Human Genomics, July 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (87th percentile)
  • High Attention Score compared to outputs of the same age and source (85th percentile)

Mentioned by

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21 X users

Citations

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110 Dimensions

Readers on

mendeley
443 Mendeley
citeulike
3 CiteULike
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Title
Validation and assessment of variant calling pipelines for next-generation sequencing
Published in
Human Genomics, July 2014
DOI 10.1186/1479-7364-8-14
Pubmed ID
Authors

Mehdi Pirooznia, Melissa Kramer, Jennifer Parla, Fernando S Goes, James B Potash, W Richard McCombie, Peter P Zandi

Abstract

The processing and analysis of the large scale data generated by next-generation sequencing (NGS) experiments is challenging and is a burgeoning area of new methods development. Several new bioinformatics tools have been developed for calling sequence variants from NGS data. Here, we validate the variant calling of these tools and compare their relative accuracy to determine which data processing pipeline is optimal.

X Demographics

X Demographics

The data shown below were collected from the profiles of 21 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 443 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 7 2%
Germany 4 <1%
United Kingdom 3 <1%
Netherlands 2 <1%
Italy 2 <1%
Norway 2 <1%
Colombia 1 <1%
Canada 1 <1%
Nigeria 1 <1%
Other 3 <1%
Unknown 417 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 110 25%
Researcher 100 23%
Student > Master 66 15%
Student > Bachelor 28 6%
Other 25 6%
Other 58 13%
Unknown 56 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 157 35%
Biochemistry, Genetics and Molecular Biology 117 26%
Medicine and Dentistry 34 8%
Computer Science 33 7%
Neuroscience 7 2%
Other 27 6%
Unknown 68 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 June 2015.
All research outputs
#3,202,387
of 25,374,917 outputs
Outputs from Human Genomics
#84
of 564 outputs
Outputs of similar age
#30,795
of 239,660 outputs
Outputs of similar age from Human Genomics
#1
of 7 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 564 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one has done well, scoring higher than 85% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 239,660 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them